A 2007 paper published in “Prescrire International” noted that thiamine deficiency is frequent in alcoholics and can lead to serious complications. Therefore, high doses of thiamine can be supplemented to compensate for poor absorption. Niacin (vitamin B-3) and pantothenic acid (vitamin B-5) can also help the body detox from alcohol, Henninger says. An easy way to get all the B vitamins is to supplement a B-complex vitamin. The 1985 Chinese Pharmacopoeia suggests 9–۱۵ grams of kudzu root per day.6 In China, standardized root extracts (10 mg tablet is equivalent to 1.5 grams of the crude root) are used to treat angina pectoris. Some sources recommend 30–۱۲۰ mg of the extract two to three times per day. A. She took kudzu-root extract (available in health-food stores). In its native China, kudzu has long been used to help people control their desire for alcohol. Drive through the countryside anywhere in the southern United States and you’re likely to see vines of kudzu smothering trees, shrubs, telephone poles, old cars, and anything else in their path.
- Rysuly MR, Azhibekova RJ Treatment of the Rennaissance-Iodine containing drug on patients with Hepatitis C. Amaty, Astana, Kazakhstan.
- An easy way to get all the B vitamins is to supplement a B-complex vitamin.
- Nor will it drastically enhance your quality of life after the first dose.
- Treatment of rats with saikosaponins 2 hours before treatment with D-galactosamine inhibited the increase in serum aspartate aminotransferase and alanine aminotransferase levels produced by damage of liver tissues .
- Specifically, in a prospective, randomized, double-blind controlled clinical trial they found no difference between Kudzu and placebo after a one month treatment period in either reducing alcohol craving and or promoting sobriety.
Ibogaine is a naturally occurring alkaloid extracted from the root of an African shrub . Preparations of the herb have been used as a stimulant in traditional African culture for centuries. Animal studies suggest that ibogaine and its primary metabolite, noribogaine, significantly reduce alcohol consumption in rats genetically engineered to prefer alcohol. In retrospect, my experience demonstrates the utility of kudzu for alcoholism. If I had been committed to using kudzu to wean off of alcohol and then quit, it might have been a very valuable part of my recovery. I did not know at the time that people also use kudzu to treat alcohol withdrawal symptoms; kudzu root for alcohol cravings nor did I care, because I did not intend to quit at the time. A small study showed that in heavy drinkers of alcohol, kudzu did result in a reduction of the number of beers consumed after 7 days of treatment. Drinking was recorded using a custom built end table that contained a digital scale beneath a ceramic tile insert in the tabletop (Ohaus model #B10P with I5S controller). Participants were instructed to always keep the beer glass on the table except when taking a sip. The scale was connected to a computer in an adjacent room that ran a customized program that sampled the scale at 5 Hz and detected any weight changes that exceeded 1 gm.
Side effects of kudzu root
Penetar DM, MacLean RR, McNeil JF, Lukas SE. Kudzu extract treatment does not increase the intoxicating effects of acute alcohol in human volunteers. Excessive alcohol consumption is a leading cause of illness worldwide (Shield et al., 2013) and has a significant impact on the health of millions people. The impact of excessive alcohol consumption results in increased healthcare costs, loss of productivity, alcohol-related crime , and motor vehicle accidents. If you are struggling with an alcohol or drug abuse problem it is prudent to consult with a mental health provider or an addiction specialist before considering any natural product supplement. Mentat™, a proprietary Ayurvedic compound herbal formula, has been found to reverse effects of acute benzodiazepine withdrawal in dependent mice, and may provide similar benefits in humans (Kulkarni 1994; Kulkarni 1992).
Have been taking Kudzu root which is supposed to reduce alcohol cravings. I’m gagging for a glass of wine.
— Rose Chowdhury (@LilysmumW) November 25, 2009
Heavy drinkers, both male and female, were given either a placebo or kudzu extract for 7 days. They were then given the opportunity to drink the beer of their choice in a naturalistic laboratory setting. Researchers monitored drinking behavior with a digital scale located in the top of an end table. This allowed them to measure the rate of drinking as well as the volume of sips. The ability of puerarin and related isoflavones to facilitate alcohol’s entry into the brain has not been systematically studied. For this mechanism to be plausible, the more rapid penetration of alcohol into the brain would have to trigger a satiety mechanism rather quickly such that the desire for the next drink is delayed—thus interrupting a binge episode. This is precisely what was observed in the present study as kudzu’s effects were evident after a single dose within a few hours of administration. Of course, it is entirely possible that any of the above mechanisms may also develop with repeated administration and complement the immediate altered absorption effect that likely explains kudzu’s rapid onset of action. The number of participants who drank each available beer during the 1.5 hour drinking session following administration of placebo or kudzu. WASHINGTON – An extract of the kudzu vine being developed to treat alcoholism may also help treat cocaine addiction, researchers at Gilead Sciences Inc reported on Sunday.
Herbal Approaches to Alcohol Dependence: Evidence and Risks
“We suspect it may work because it increases blood flow,” he says. “It may deliver alcohol to the brain’s reward center faster. So you get an effect sooner; therefore, you don’t drink as much.” “When they were treated with puerarin they drank about a beer less than when they were treated with placebo,” he says. Before the second, they took either 1,200 milligrams of puerarin or identical-looking placebo pills for a week. They came to the lab and could drink as much as they wanted, up to six beers. In Chinese pharmacy books, kudzu is listed as a possible treatment for alcohol-related hangovers and cravings, Penetar tells WebMD. They found how it works — by raising levels of a compound called tetrahydropapaveroline or THP. Cocaine cravings make levels of a brain chemical called dopamine soar and THP interferes with this.
However, this effect by daidzin is not like a classical ALDH-2 inhibitor because it does not also inhibit the cytosolic form, of liver ALDH-1, which is a very efficient catalyst of acetaldehyde oxidation. Thus daidzin can suppress ethanol intake of this species without blocking acetaldehyde metabolism. There are many ways, both medical and traditional, that are used to treat alcohol abuse or dependence. In China, kudzu root extract has been commonly used to reduce, but not eliminate, alcohol consumption and dependence. Despite its history, the mechanism of action for kudzu extract is still unknown, and that is what the current research explores.
“There is no effective treatment for cocaine addiction despite extensive knowledge of the neurobiology of drug addiction,” wrote Lina Yao, Ivan Diamond and colleagues. James Lake, M.D., a clinical assistant professor at the University of Arizona College of Medicine, works to transform mental health care through the evidence-based uses of alternative therapies. Kudzu is used in modern Chinese medicine as a treatment for angina. Standardized root tablets are sometimes used for angina pectoris. For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being. But promising as it is for rats, it remains to be seen whether the drug is safe and effective for people.
In fact, even a single dose of kudzu extract may be helpful if you’re looking to reduce your drinking. Kudzu root gets some serious rep’ for helping folks ease off of the booze. One small study looking at the effects of kudzu in a group of men that reported drinking between 22 and 35 drinks per week shows promising results. After consuming kudzu extract kudzu root for alcohol cravings for 4 weeks, the participants reduced their number of weekly alcoholic beverages by at least a third. The participants reported their desire for and consumption of alcohol for the duration of the study. Researchers found that the kudzu extract had no effect on alcohol cravings, but it reduced the number of weekly alcoholic drinks by 34–۵۷% .
Clinical & Medical Journals
Although I’m sure it would have helped me detoxify, I did not use kudzu after I quit drinking. My experience was limited to an experiment that I did years ago to see if taking the herb would reduce my drinking levels. I will discuss how kudzu works, my experience with using powdered kudzu root for alcoholism, and recommendations for taking kudzu. Lukas recruited 14 men and women in their 20s to spend four 90-minute sessions consuming beer and watching TV. Researchers selected people who said they regularly consumed Sober House three to four drinks per day. Changes in the chemistry of 6″-malonyl-7′-β-glucosyldaidzein, a major soybean component, during food processing. Dry heating of 6″-malonyl-7′-β-glucosyldaidzein leads to decarboxylation to 6″-acetyl-7′-β-glucosyldaidzein . Heated, aqueous extraction of soybeans to make soy milk and tofu, removes the malonyl group to make daidzin . Fermentation can also lead to hydrolysis of the glucosyl group . Daidzein and glycitein in soy and kudzu, and formononetin and biochanin A in red clover.